Vitamin B12
Typical Dosing Protocols (Research/Compounded Use Only) – Vitamin B12
Common protocol: 500–1,000 mcg subcutaneously or intramuscularly once weekly (most popular is 1,000 mcg weekly). Many users start with 1,000 mcg weekly for 4–8 weeks, then switch to maintenance of 500–1,000 mcg every 1–2 weeks.
Other reported ranges:
Loading phase: 1,000 mcg daily or every other day for 1–2 weeks (severe deficiency)
Maintenance: 500–1,000 mcg weekly or bi-weekly
High-dose protocols: Up to 2,000–5,000 mcg weekly in some wellness settings
Reconstitution / Administration Notes:
Methylcobalamin or Hydroxocobalamin forms are most common.
Subcutaneous or intramuscular injection using an insulin syringe.
Common injection sites: abdomen (subQ) or deltoid/glute (IM).
No reconstitution needed for most pre-filled or standard vials/ampoules.
Dosing is highly individualized based on deficiency levels, labs, and response—consult a qualified healthcare provider for personalized guidance and blood work monitoring. This is for informational purposes only.
