GLP-2
Typical Dosing Protocols (Research/Compounded Use Only) – Tirzepatide
Common protocol: 2.5 mg subcutaneously once weekly for the first 4 weeks, then increase by 2.5 mg every 4 weeks as tolerated (e.g., to 5 mg, 7.5 mg, 10 mg, 12.5 mg, or up to 15 mg weekly). Maintenance doses are typically 5–15 mg once weekly depending on response and goals (weight management or metabolic support).
Other reported ranges: 2.5–15 mg once weekly; some protocols start lower (1.5–2.5 mg) or titrate more slowly to minimize side effects. Titration is gradual over 4+ weeks per step; long-term use is common rather than short cycles, with ongoing monitoring.
Reconstitution example (for a typical 10 mg vial): Add 1 mL bacteriostatic water (yielding 10 mg/mL).
2.5 mg = 0.25 mL (25 units on U-100 insulin syringe)
5 mg = 0.50 mL (50 units)
7.5 mg = 0.75 mL (75 units)
10 mg = 1.0 mL (100 units)
Administration: Subcutaneous injection (abdomen, thigh, or upper arm); any time of day, with or without food. Rotate injection sites weekly.
Dosing is highly individualized based on goals and response—consult a qualified healthcare provider experienced with peptides for personalized guidance. This is for informational purposes only.
